Product Description
St. John's Wort Extract Hypericins 0.3% UV/HPLC
| Product Name |
St. John's Wort Extract Hypericins |
| Botanical Name |
Hypericum perforatum L. |
| Part of Used |
Herb |
| Specification |
Standardized as Hypericins |
| Applied Industries |
Pharmaceuticals, Nutraceuticals and Cosmeceuticals |
St. John's Wort Extract Reviews
Extracts of St John's wort or Hypericum perforatum, a perennial herb with small yellow flowers, are widely available in pharmacies and health food stores. Historically, St John's wort has been used for a variety of conditions including abdominal pains, alcoholism, earaches and menopausal complaints. However, the most common reason for using St John's wort is depression and low mood. Patients will commonly be advised to take St John's wort when presenting to health food stores with symptoms of depression. While high-quality, controlled studies found it to be effective for the treatment of mildto- moderate depression, it has not been included in mainstream treatment guidelines because of uncertainty about appropriate doses, persistence of effect, variation in the nature of preparations and potentially serious drug interactions.
Chemical Constitution of St. John's Wort Extract
Hypericins, which are the most important ingredients in St. John's Wort Powder Extract that are studied by lots of scientists all over the world. St. John's Wort contains protohypericin, protopseudohypericin and cyclopseudohypericin. All these occur mainly in the flowering parts of the plant and especially located in the dark glands. Protohypericin and protopseudohypericin are considered to be the biosynthetic precursors of hypericin and pseudohypericin, respectively, from which the latter derive on exposure to light. Also pseudohypericin is likely to be transformed to cyclopseudohypericin. Protohypericin, protopseudohypericin and cyclopseudohypericin are detected in lower concentrations and are included in the analytical term "total hypericins" or "total naphthodianthrones". In general, the content of pseudohyhypericin (0.03-0.34%) is higher from that of hypericin (0.03-0.09%) two to four times, depending on the variety.
Health Benefits of St. John's Wort Extract
Although researches on the health benefits of taking St. John's Wort Powder Extract are limited, some studies suggest that St. John's Wort Powder Extract may offer certain health benefits. Here's a look at several key study findings:
Anxiety and Depression
Studies suggest that St. John's Wort has significant amounts of hyperforin and hypericin which may raise the release of neurotransmitters (dopamine, norepinephrine, and serotonin) that modulate brain signals between cells and play an important role in the optimal functionality of our nervous system. Hypericin in St. John's Wort may also be capable of inhibiting a bodily chemical, monoamine oxidase, which is associated with anxiety and depression. As a result, this herb may induce the sense of well being which can help with mild to moderate depression, mood swings, wintertime blues, low energy levels, and chronic fatigue.
Parkinson's Disease
It is believed that a dopamine dysfunction is one of the causes of Parkinson's disease and schizophrenia. Some studies suggest that St. John's Wort may raise the levels of the neurotransmitter dopamine. Studies also suggest that antioxidant activity of the herb may help with neural degeneration associated with the onset of Parkinson's disease. However, further studies are required to prove the extent of effectiveness of the herb. However, simply drinking one cup of St. John's Wort tea or one capsule of its extract regularly with a meal may inhibit the development of Parkinson's disease in people at risk of developing it.
Wounds and Bruises
St. John's Wort has antibacterial and analgesic activity. Therefore, a balm, oil, or poultice made with St. John's Wort flowers and leaves may help heal cuts, wounds, insect bites, boils, and bruises. St. John's Wort oil can be made by frying 1/2 cup of dried flowers and leaves of the herb in 2 tbsp of mustard oil. Leave the flowers and leaves in the oil and let the mixture cool down. Then add 1/3 cup of Extra Virgin Olive Oil to the prepared St. John's Wort oil. Apply it 3-4 times on a wound throughout the day. The prepared oil can be stored in an air tight container in a cool and dark place for emergency use.
St. John's Wort Extract Side effects
It is not safe to take St. John's Wort Powder Extract with a prescription antidepressant. St. John's Wort Powder Extract is effective for depression. However, as its mechanism of action is similar to that of many common antidepressants that increase levels of serotonin and noradrenaline in the brain, combined therapy can increase the risk of symptoms associated with serotonin toxicity (ie hyperreflexia, tremor, sweating, agitation, confusion, clonus and diarrhoea).
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